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599-64-4

599-64-4 structure
599-64-4 structure
  • Name: 4-cumylphenol
  • Chemical Name: 4-cumylphenol
  • CAS Number: 599-64-4
  • Molecular Formula: C15H16O
  • Molecular Weight: 212.28700
  • Catalog: Chemical reagent Organic reagent Aromatic alcohol
  • Create Date: 2018-02-26 08:00:00
  • Modify Date: 2024-01-02 16:26:57
  • 4-Cumylphenol is a polycarbonate chain terminator. 4-Cumylphenol is widely used as a material for polycarbonate plastics, surfactants, fungicides and preservatives. 4-Cumylphenol also induces lipid accumulation in mouse adipocytes[1][2][3].

Name 4-cumylphenol
Synonyms P-CUMYLPHENOL
AURORA 4778
paracumilphenol
PARA-CUMYLPHENOL
PCP
Cumyl phenol
EINECS 209-968-0
MFCD00002365
Description 4-Cumylphenol is a polycarbonate chain terminator. 4-Cumylphenol is widely used as a material for polycarbonate plastics, surfactants, fungicides and preservatives. 4-Cumylphenol also induces lipid accumulation in mouse adipocytes[1][2][3].
Related Catalog
In Vitro 4-Cumylphenol (1, 5, 10, 20, 40 µM; 6 days) increase lipid accumulation in 3 T3-L1 cells[3]. Cell Viability Assay[3] Cell Line: 3 T3-L1 cells Concentration: 1, 5, 10, 20, 40 µM Incubation Time: 6 days Result: Increase lipid accumulation, which peaked at10 μM with a 204% increase.
References

[1]. Yue W, et al. Biodegradation of bisphenol-A polycarbonate plastic by Pseudoxanthomonas sp. strain NyZ600. J Hazard Mater. 2021 Aug 15;416:125775.

[2]. Chiha M, et al. Sonolytic degradation of endocrine disrupting chemical 4-cumylphenol in water. Ultrason Sonochem. 2011 Sep;18(5):943-50.

[3]. Ramskov Tetzlaff CN, Svingen T, et al. Bisphenols B, E, F, and S and 4-cumylphenol induce lipid accumulation in mouse adipocytes similarly to bisphenol A. Environ Toxicol. 2020 May;35(5):543-552.

Density 1,115 g/cm3
Boiling Point 335 °C
Melting Point 72-75 °C
Molecular Formula C15H16O
Molecular Weight 212.28700
Flash Point 160 °C
Exact Mass 212.12000
PSA 20.23000
LogP 3.71810
Index of Refraction 1.587
Stability Stable. Incompatible with oxidizing agents, acid chlorides, acid anhydrides. Combustible.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SL1942450
CHEMICAL NAME :
Phenol, p-(alpha,alpha-dimethylbenzyl)-
CAS REGISTRY NUMBER :
599-64-4
BEILSTEIN REFERENCE NO. :
1870517
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C15-H16-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
335 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 12(12),44,1968
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S24/25-S37/39-S26
RIDADR NONH for all modes of transport
RTECS SL1942450