Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Ethyl vanillate
Price: ￥608.0/100g ￥198.0/25g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Ethyl vanillate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Ethyl 4-hydroxy-3-methoxybenzoate
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

617-05-0

617-05-0 structure

Name: Ethyl vanillate
Chemical Name: Ethyl 4-hydroxy-3-methoxybenzoate
CAS Number: 617-05-0
Molecular Formula: C₁₀H₁₂O₄
Molecular Weight: 196.200
Catalog: Organic raw materials Carboxylic compounds and derivatives Carboxylic esters and their derivatives
Create Date: 2018-05-07 08:00:00
Modify Date: 2024-01-02 19:56:21
Ethyl Vanillate is a fungicidal agent. Ethyl Vanillate inhibits 17β-HSD2 with an IC50 1.3 µM[1][2].

Name	Ethyl 4-hydroxy-3-methoxybenzoate
Synonyms	3-methoxy-4-hydroxybenzoic acid ethyl ester Ethyl vanillate Ethyl 4-hydroxy-3-methoxybenzoate EINECS 210-503-9 Benzoic acid,4-hydroxy-3-methoxy-,ethyl ester Benzoic acid, 4-hydroxy-3-methoxy-, ethyl ester 4-Hydroxy-3-methoxybenzoic acid ethyl ester 3-methoxy-4-hydroxy-ethyl benzoate VANILLIC ACID,ETHYL ESTER Ethyl-4-hydroxy-3-methoxybenzolcarboxylat ethyl-3-methoxy-4-hydroxybenzoate MFCD00017269

Description	Ethyl Vanillate is a fungicidal agent. Ethyl Vanillate inhibits 17β-HSD2 with an IC50 1.3 µM[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
Target	IC50: 1.3 µM (17β-HSD2)[1]
References	[1]. Engeli RT, et al. Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases. Int J Mol Sci. 2017 Sep 19;18(9). pii: E2007. [2]. COHEN R, et al. Four new fungicides for Coccidioides immitis: 1. Sodium caprylate. 2. Ethyl vanillate 3. Fradicin. 4. Thiolutin. Arch Pediatr. 1951 Jun;68(6):259-64.

Density	1.2±0.1 g/cm3
Boiling Point	292.0±0.0 °C at 760 mmHg
Melting Point	43-45°C
Molecular Formula	C₁₀H₁₂O₄
Molecular Weight	196.200
Flash Point	122.4±15.8 °C
Exact Mass	196.073563
PSA	55.76000
LogP	2.07
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.528

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YW5425000

CHEMICAL NAME :: Vanillic acid, ethyl ester

CAS REGISTRY NUMBER :: 617-05-0

BEILSTEIN REFERENCE NO. :: 2100025

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H12-O4

MOLECULAR WEIGHT :: 196.22

WISWESSER LINE NOTATION :: 2OVR DQ CO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59 Volume(issue)/page/year: 1,138,1955

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#06395

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59 Volume(issue)/page/year: 1,138,1955

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Hazard Codes	Xn
Risk Phrases	22-36/37/38
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
RTECS	YW5425000
HS Code	2918990090

121-34-6

617-05-0

Literature: US6638928 B1, ;

64-17-5

9005-53-2

617-05-0

18256-48-9

Detail

Literature: US2010/121110 A1, ; Page/Page column 5-8 ;

64-17-5

121-34-6

~81%

617-05-0

Literature: Kumar, Rakesh; Ramachandran, Uma; Srinivasan, Krishnamoorthy; Ramarao, Poduri; Raichur, Suryaprakash; Chakrabarti, Ranjan Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 13 p. 4279 - 4290

121-34-6

75-03-6

~74%

617-05-0

Literature: Lee, Jong Chan; Choi, Youngsup Synthetic Communications, 1998 , vol. 28, # 11 p. 2021 - 2026

121-34-6

78-39-7

~88%

617-05-0

Literature: Lee, Jong Chan; Song, In-Goul; Park, Jin Young Synthetic Communications, 2002 , vol. 32, # 14 p. 2209 - 2213

1847-84-3

617-05-0

Literature: Journal of Organic Chemistry, , vol. 37, p. 3160 - 3163

90-05-1

617-05-0

Literature: Journal of Organic Chemistry, , vol. 37, p. 3160 - 3163

1847-84-3

35030-98-9

617-05-0

Literature: Journal of Organic Chemistry, , vol. 37, p. 3160 - 3163

Precursor 6
121-34-6 64-17-5 75-03-6 78-39-7
1847-84-3 90-05-1
DownStream 6
100377-63-7 1486-53-9 7152-90-1 196194-41-9
97966-31-9 98033-66-0

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

617-05-0	898792-76-2
175394-01-1	362669-45-2
101616-76-6	302964-01-8
898777-81-6	135072-31-0
110166-71-7	110166-76-2