118414-82-7
118414-82-7 structure
- Name: MK886
- Chemical Name: 3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acid
- CAS Number: 118414-82-7
- Molecular Formula: C27H34ClNO2S
- Molecular Weight: 472.08
- Catalog: Signaling Pathways Immunology/Inflammation FLAP
- Create Date: 2018-12-21 01:18:00
- Modify Date: 2024-01-08 11:59:15
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MK886 is a 5-lipoxygenase-activating protein inhibitor and a leukotriene biosynthesis inhibitor (IC50=2.5 nM).
| Name | 3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acid |
|---|---|
| Synonyms |
Sodium 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-isopropyl-1H-indol-2-yl]-2,2-dimethylpropanoate
1H-Indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-α,α-dimethyl-5-(1-methylethyl)-, sodium salt (1:1) Pizotifenum Pizotifene SIN-1 chloride PIZOTYLINE Sandomygran BC-105 Pizotifeno Litec Pizotifen Sandomigran Polomigran Sodium 3-{1-(4-chlorobenzyl)-5-isopropyl-3-[(2-methyl-2-propanyl)sulfanyl]-1H-indol-2-yl}-2,2-dimethylpropanoate MK-886 |
| Description | MK886 is a 5-lipoxygenase-activating protein inhibitor and a leukotriene biosynthesis inhibitor (IC50=2.5 nM). |
|---|---|
| Related Catalog | |
| References |
| Density | 1.14g/cm3 |
|---|---|
| Boiling Point | 623.4ºC at 760mmHg |
| Melting Point | 295-297ºC |
| Molecular Formula | C27H34ClNO2S |
| Molecular Weight | 472.08 |
| Flash Point | 330.8ºC |
| PSA | 70.36000 |
| LogP | 6.67560 |
| Vapour Pressure | 2.11E-16mmHg at 25°C |
| Index of Refraction | 1.58 |
| Storage condition | -20℃ |
| WGK Germany | 3 |
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