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42265-67-8

42265-67-8 structure
42265-67-8 structure
  • Name: 4-(TERT-BUTYL)-2-CHLOROANILINE
  • Chemical Name: 4-tert-butyl-2-chloroaniline
  • CAS Number: 42265-67-8
  • Molecular Formula: C10H14ClN
  • Molecular Weight: 183.67800
  • Create Date: 2018-04-03 08:00:00
  • Modify Date: 2024-02-01 08:01:16

Name 4-tert-butyl-2-chloroaniline
Synonyms 4-t-Butyl-2-chloroaniline
2-chloro-4-t-butylaniline
2-Chlor-4-t-butylanilin
Aniline,4-tert-butyl-2-chloro
2-chloro-4-tert-butyl-phenylamine
4-tert-Butyl-2-chlor-anilin
4-tert-butyl-2-chloro-aniline
Density 1.078g/cm3
Boiling Point 246.9ºC at 760mmHg
Molecular Formula C10H14ClN
Molecular Weight 183.67800
Flash Point 103.1ºC
Exact Mass 183.08100
PSA 26.02000
LogP 3.80090
Index of Refraction 1.543
Name: 4-(tert-Butyl)-2-chloroaniline Material Safety Data Sheet
Synonym:
CAS: 42265-67-8
Section 1 - Chemical Product MSDS Name:4-(tert-Butyl)-2-chloroaniline Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
42265-67-8 3,4-Dichlorophenylboronic acid 97+% unlisted
Hazard Symbols: XN
Risk Phrases: 20/21/22 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
Harmful if inhaled. Causes respiratory tract irritation.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 42265-67-8: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Color: Colourless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 84 deg C @0.1mm Hg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H14ClN
Molecular Weight: 183.68

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Bases, chlorates, finely powdered metals, iron, nitrates, nitrites, perchlorates, permanganates, phosphorus, potassium chlorates, steel, zinc, hydrogen peroxide, cesium acetylene carbide, cyanides (e.g.
potassium cyanide, sodium cyanide), nitromethane, phosphorus trioxide, azides, iodides, benzene, carbides, moisture, fulminates, picrates, organic materials, mercuric nitride, strong dehydrating agents, alkali halides, cyclopentadiene, cyclpentanone oxime, nitroaryl amines, lithium silicides, trihydroxydiamino phosphate.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 42265-67-8 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
3,4-Dichlorophenylboronic acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2810
Packing Group: III
IMO
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing Group: III
RID/ADR
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing group: III

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 42265-67-8: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 42265-67-8 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 42265-67-8 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Hazard Codes Xi
Risk Phrases 20/21/22-36/37/38
Safety Phrases 26-36/37/39
HS Code 2921420090

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42265-67-8 structure

42265-67-8

Literature: PHARMESTE S.R.L.; NAPOLETANO, Mauro; TREVISANI, Marcello; PAVANI, Maria Giovanna; FRUTTAROLO, Francesca Patent: WO2011/120604 A1, 2011 ; Location in patent: Page/Page column 111; 132 ; WO 2011/120604 A1

~46%

42265-67-8 structure

42265-67-8

Literature: Ezquerra, Jesus; Pedregal, Concepcion; Lamas, Carlos; Barluenga, Jose; Perez, Marta; Garcia-Martin, Miguel Angel; Gonzalez, Jose M. Journal of Organic Chemistry, 1996 , vol. 61, # 17 p. 5804 - 5812

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42265-67-8 structure

42265-67-8

Literature: Morton; Claff Journal of Organic Chemistry, 1956 , vol. 21, p. 736

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42265-67-8 structure

42265-67-8

Literature: Bartlett,P.D. et al. Journal of the American Chemical Society, 1968 , vol. 90, p. 2049 - 2056

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42265-67-8 structure

42265-67-8

Literature: O'Meara, Jeff A.; Jakalian, Araz; LaPlante, Steven; Bonneau, Pierre R.; Coulombe, Rene; Faucher, Anne-Marie; Guse, Ingrid; Landry, Serge; Racine, Jennifer; Simoneau, Bruno; Thavonekham, Bounkham; Yoakim, Christiane Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 12 p. 3362 - 3366
HS Code 2921420090
Summary HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%