942047-63-4

942047-63-4 structure
942047-63-4 structure
  • Name: Meloxicam D4
  • Chemical Name: 4-hydroxy-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-2-(trideuteriomethyl)-1λ6,2-benzothiazine-3-carboxamide
  • CAS Number: 942047-63-4
  • Molecular Formula: C14H10D3N3O4S2
  • Molecular Weight: 351.40100
  • Catalog: analytical chemistry Standard Analytical standard
  • Create Date: 2018-07-25 08:35:36
  • Modify Date: 2024-01-14 11:25:20
  • Meloxicam D4 is deuterium labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively[1].

Name 4-hydroxy-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-2-(trideuteriomethyl)-1λ6,2-benzothiazine-3-carboxamide
Synonyms Parocin-d3
Metacam-d3
Movalis-d3
Movatec-d3
4-Hydroxy-2-(methyl-d3)-1,1-dioxo-benzo[e]-1,2-thiazine-3-carboxylic acid (5-methyl-2-thiazolyl)amide
Mobic-d3
Mobicox-d3
Meloxicam-d3
Description Meloxicam D4 is deuterium labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively[1].
Related Catalog
References

[1]. Lazer ES, et al. Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. J Med Chem. 1997 Mar 14;40(6):980-9.

Melting Point 249-251°C
Molecular Formula C14H10D3N3O4S2
Molecular Weight 351.40100
Exact Mass 351.03500
PSA 139.71000
LogP 3.61910
Storage condition -20°C Freezer
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn
Risk Phrases 22
RIDADR UN 2811 6.1/PG 3