569-80-2

569-80-2 structure

Name: penduletin
Chemical Name: 5-hydroxy-2-(4-hydroxyphenyl)-3,6,7-trimethoxychromen-4-one
CAS Number: 569-80-2
Molecular Formula: C₁₈H₁₆O₇
Molecular Weight: 344.32
Catalog: Natural product Flavonoids
Create Date: 2017-12-11 21:03:24
Modify Date: 2024-01-10 11:35:55
Penduletin is a flavone, that can be isolated from Brickelia pendula and Vitex negundo. Penduletin shows anticancer activity. Penduletin induces apoptosis in the cancer cells through ROS generation[1][2].

Name	5-hydroxy-2-(4-hydroxyphenyl)-3,6,7-trimethoxychromen-4-one
Synonyms	5,4'-Dihydroxy-3,6,7-trimethoxyflavone 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-3,6,7-trimethoxy- 6-OH-kaempferol-3,6,7-trimethylether 5-Hydroxy-2-(4-hydroxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one Penduletin 5-Hydroxy-2-(4-hydroxyphenyl)-3,6,7-trimethoxy-4H-chromen-4-one 4',5-dihydroxy-3,6,7-trimethoxy-flavone

Description	Penduletin is a flavone, that can be isolated from Brickelia pendula and Vitex negundo. Penduletin shows anticancer activity. Penduletin induces apoptosis in the cancer cells through ROS generation[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Flores S E, et al.The structure of pendulin and penduletin: a new flavonol glucoside isolated from brickelia pendula[J].Tetrahedron, 1958, 2(3-4):308-315. [2]. Vo GV, et al. In silico and in vitro studies on the anti-cancer activity of artemetin, vitexicarpin and penduletin compounds from Vitex negundo. Saudi Pharm J. 2022 Sep;30(9):1301-1314.

Hazard Codes	Xi

Precursor 0
DownStream 1
4472-73-5