78832-54-9

78832-54-9 structure

78832-54-9 structure

Name: 2-Naphthol-d7
Chemical Name: 1,3,4,5,6,7,8-heptadeuterionaphthalen-2-ol
CAS Number: 78832-54-9
Molecular Formula: C₁₀HD₇O
Molecular Weight: 151.21300
Catalog: Research Areas Others
Create Date: 2018-10-05 19:05:34
Modify Date: 2024-01-05 14:59:56
2-Naphthol-d7 is the deuterium labeled 2-Naphthol[1]. 2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2)[2].

Name	1,3,4,5,6,7,8-heptadeuterionaphthalen-2-ol
Synonyms	MFCD01074243 2-Naphthol-1,3,4,5,6,7,8-d7 2-naphthol-d7

Description	2-Naphthol-d7 is the deuterium labeled 2-Naphthol[1]. 2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2)[2].
Related Catalog	Research Areas >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Kapuci M, et al. Determination of cytotoxic and genotoxic effects of naphthalene, 1-naphthol and 2-naphthol on human lymphocyte culture. Toxicol Ind Health. 2014 Feb;30(1):82-9.

Density	1.239g/cm3
Boiling Point	285-286ºC(lit.)
Melting Point	120-122ºC(lit.)
Molecular Formula	C₁₀HD₇O
Molecular Weight	151.21300
Flash Point	144ºC
Exact Mass	151.10100
PSA	20.23000
LogP	2.54540
Index of Refraction	1.677

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302 + H332-H400
Precautionary Statements	P261-P301 + P312 + P330
Hazard Codes	Xn: Harmful;
Risk Phrases	22-36/37/38
Safety Phrases	26-36
RIDADR	UN 3077 9 / PGIII

Precursor 0
DownStream 1
1014689-18-9