83881-46-3
83881-46-3 structure
- Name: Cetirizine methyl ester
- Chemical Name: methyl 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetate
- CAS Number: 83881-46-3
- Molecular Formula: C22H27ClN2O3
- Molecular Weight: 402.91400
- Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
- Create Date: 2017-06-23 06:01:41
- Modify Date: 2024-01-08 18:12:34
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Cetirizine methyl ester is an impurity of Cetirizine (HY-17042). Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1].
| Name | methyl 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetate |
|---|---|
| Synonyms |
methyl [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetate
(2-{4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl}ethoxy)acetic acid methyl ester methyl-2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetate Cetirizine Methyl Ester Cetirizine Methanol Adduct |
| Description | Cetirizine methyl ester is an impurity of Cetirizine (HY-17042). Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1]. |
|---|---|
| Related Catalog |
| Molecular Formula | C22H27ClN2O3 |
|---|---|
| Molecular Weight | 402.91400 |
| Exact Mass | 402.17100 |
| PSA | 42.01000 |
| LogP | 3.11240 |
|
~90%
83881-46-3 |
| Literature: Chemagis Ltd. Patent: EP952153 A2, 1999 ; |
|
~96%
83881-46-3 |
| Literature: HANLIM PHARMACEUTICAL CO., LTD. Patent: WO2005/73207 A1, 2005 ; Location in patent: Page/Page column 8 ; |
|
~97%
83881-46-3 |
| Literature: Pflum, Derek A.; Wilkinson, H. Scott; Tanoury, Gerald J.; Kessler, Donald W.; Kraus, Hali B.; Senanayake, Chris H.; Wald, Stephen A. Organic Process Research and Development, 2001 , vol. 5, # 2 p. 110 - 115 |
| Precursor 4 | |
|---|---|
| DownStream 0 | |