- BioBioPha
- China
- Product Name: (+)-Cedrol
- Price: ￥Inquiry/50mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: (+)-Cedrol
- Price: ￥288.0/25g ￥98.0/5g ￥158.0/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Cedrol
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
77-53-2
77-53-2 structure
- Name: (+)-Cedrol
- Chemical Name: cedrol
- CAS Number: 77-53-2
- Molecular Formula: C15H26O
- Molecular Weight: 222.366
- Catalog: Flavors and spices Synthetic spice Alcoholic spice Terpene alcohol
- Create Date: 2018-05-26 08:00:00
- Modify Date: 2024-01-02 17:15:38
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Cedrol is a bioactive sesquiterpene, a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes[1]. Cedrol is found in cedar essential oil and poetesses anti-septic, anti-inflammatory, anti-spasmodic, tonic, astringent, diuretic, sedative, insecticidal, and anti-fungal activities[2].
| Name | cedrol |
|---|---|
| Synonyms |
8bH-Cedran-8-ol
EINECS 201-035-6 Cedarwood oil alcohols (8α)-Cedran-8-ol Cedar camphor (1S,2R,5S,7R,8R)-2,6,6,8-Tetramethyltricyclo[5.3.1.0]undecan-8-ol 8betaH-Cedran-8-ol EUDESMOL 1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-, (3R,3aS,6R,7R,8aS)- (1S,2R,5S,7R,8R)-2,6,6,8-Tétraméthyltricyclo[5.3.1.0]undécan-8-ol Cypress camphor 8βH-cedran-8-ol [3R-(3a,3ab,6a,7b,8aa)]-Octahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-6-ol Cedrol MFCD00062952 |
| Description | Cedrol is a bioactive sesquiterpene, a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes[1]. Cedrol is found in cedar essential oil and poetesses anti-septic, anti-inflammatory, anti-spasmodic, tonic, astringent, diuretic, sedative, insecticidal, and anti-fungal activities[2]. |
|---|---|
| Related Catalog | |
| Target |
CYP2B6; CYP3A4; CYP2C8; CYP2C9; CYP2C19[1] |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 277.2±8.0 °C at 760 mmHg |
| Melting Point | 55-59 °C(lit.) |
| Molecular Formula | C15H26O |
| Molecular Weight | 222.366 |
| Flash Point | 115.5±10.9 °C |
| Exact Mass | 222.198364 |
| PSA | 20.23000 |
| LogP | 4.77 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.519 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | PB7728666 |
| HS Code | 2906199090 |
|
~%
77-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 83, p. 3114 - 3125 |
|
~%
77-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 83, p. 3114 - 3125 |
|
~%
77-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 83, p. 3114 - 3125 |
|
~%
77-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 83, p. 3114 - 3125 |
|
~%
77-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 83, p. 3114 - 3125 |
|
~%
77-53-2 |
| Literature: Journal of the American Chemical Society, , vol. 83, p. 3114 - 3125 |
| Precursor 5 | |
|---|---|
| DownStream 6 | |
| HS Code | 2906299090 |
|---|---|
| Summary | 2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |