Dichlorophen

Names

[ CAS No. ]:
97-23-4

[ Name ]:
Dichlorophen

[Synonym ]:
2,2'-Dihydroxy-5,5'-dichlorodiphenylmethane
Gefir
DDM
2,2'-Methylenebis(4-chlorophenol)
Dichlorofen
Bis[5-chloro-2-hydroxyphenyl]methane
Halenol
Preventol G-D
Di[5-chloro-2-hydroxyphenyl]methane
Phenol, 2,2'-methylenebis[4-chloro-
2,2’-methylenebis[4-chlorophenol]
DDDM
Fungo
EINECS 202-567-1
dichlorophen
G 4
Palacel
5,5'-dichloro-2,2'-dihydroxydiphenylmethane
Korium
MFCD00002322
2,2'-Methylenebis[4-chlorophenol]
Dichlorophene
4-06-00-06658 (Beilstein Handbook Reference)
2,2’-methylenebis(4-chlorophenol)
Diphentane 70
G-4
Trivex
Di-phenthane-70
Hyosan
4,4’-dichloro-2,2’-methylenediphenol
Dichloorfeen
2,2'-methanediylbis(4-chlorophenol)

Biological Activity

[Description]:

Dichlorophen is an anticestodal agent.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Parasite

Research Areas >> Infection

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
418.7±40.0 °C at 760 mmHg

[ Melting Point ]:
168-172 °C(lit.)

[ Molecular Formula ]:
C₁₃H₁₀Cl₂O₂

[ Molecular Weight ]:
269.123

[ Flash Point ]:
207.0±27.3 °C

[ Exact Mass ]:
268.005798

[ PSA ]:
40.46000

[ LogP ]:
4.62

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.650

[ Stability ]:
Stable. Incompatible with strong bases, strong oxidizing agents.

[ Water Solubility ]:
<0.1 g/100 mL at 22 ºC

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SM0175000

CHEMICAL NAME :: Phenol, 2,2'-methylenebis(4-chloro-

CAS REGISTRY NUMBER :: 97-23-4

BEILSTEIN REFERENCE NO. :: 1884514

LAST UPDATED :: 199710

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C13-H10-Cl2-O2

MOLECULAR WEIGHT :: 269.13

WISWESSER LINE NOTATION :: QR DG B1R BQ EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1506 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 150 ug/plate

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 19(Suppl 21),2,1992 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84582 No. of Facilities: 855 (estimated) No. of Industries: 7 No. of Occupations: 7 No. of Employees: 3398 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84582 No. of Facilities: 441 (estimated) No. of Industries: 4 No. of Occupations: 8 No. of Employees: 4290 (estimated) No. of Female Employees: 2030 (estimated)

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319-H400

[ Precautionary Statements ]:
P273-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R22;R36;R50/53

[ Safety Phrases ]:
S26-S60-S61

[ RIDADR ]:
UN 3077 9/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
SM0175000

[ Packaging Group ]:
III

[ Hazard Class ]:
9

[ HS Code ]:
2908199022

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2908199022

[ Summary ]:
2908199022 2,2'-methylenebis(4-chlorophenol)。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:0.0%。MFN tarrif:5.5%。general tariff:30.0%

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