styrene glycol

Names

[ CAS No. ]:
93-56-1

[ Name ]:
styrene glycol

[Synonym ]:
1-PHENYL-1 2-ETHANEDIOL
1-PHENYL-1,2-ETHANEDIOL FOR SYNTHESIS
EINECS 202-258-1
.alpha.,.beta.-Dihydroxyethylbenzene
Styryl alcohol
1-Pheny-1,2-Ethanediol
rac Styrene Glycol
Fenylglycol
Styrolyl alcohol
1,2-Ethanediol, 1-phenyl-
1-Phenyl-1,2-ethanediol
Phenylethanediol
PHENYL-1 2-ETHANEDIOL
(+/-)-1-PHENYL-1,2-ETHANEDIOL
styren glycol
styrene glycol
'STYROLGLYKOL'
1,2-dihydroxyethylbenzene
(±)-Styrene glycol
phenylethylene glycol
MFCD00003546
1-Phenylethane-1,2-diol

Biological Activity

[Description]:

1-Phenylethane-1,2-diol is a typical benzyl diol compound. 1-Phenylethane-1,2-diol can be oxidized to hydroxyl ketone (2-hydroxy-1-phenylethan-1-one) selectively with variety of catalysts, including organocatalysts, metal complexes, non-noble metal oxides, bimetallics[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Fangwei Zhang, et al. Oxidation of 1-Phenylethane-1,2-Diol to 2-Hydroxy-1-Phenylethan-1-One Catalyzed by Gold Nanocrystals. ChemistrySelect. Volume 3, Issue 48 p. 13638-13640

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
273.5±0.0 °C at 760 mmHg

[ Melting Point ]:
61-67ºC

[ Molecular Formula ]:
C₈H₁₀O₂

[ Molecular Weight ]:
138.164

[ Flash Point ]:
145.7±16.4 °C

[ Exact Mass ]:
138.068085

[ PSA ]:
40.46000

[ LogP ]:
0.04

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.573

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KI2500000

CHEMICAL NAME :: 1,2-Ethanediol, 1-phenyl-

CAS REGISTRY NUMBER :: 93-56-1

BEILSTEIN REFERENCE NO. :: 1306723

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H10-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,215,1986

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
KI2500000

[ HS Code ]:
29062900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2906299090

[ Summary ]:
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Enhancement of Candida parapsilosis catalyzing deracemization of (R,S)-1-phenyl-1,2-ethanediol to its (S)-enantiomer by a highly productive "two-in-one" resin-based in situ product removal strategy.

Bioresour. Technol. 101(21) , 8461-3, (2010)

In this study, a highly efficient process for Candida parapsilosis-catalyzed deracemization of racemic 1-phenyl-1,2-ethanediol (PED) was described, based on a resin-based in situ substrate feeding and...

Biosynthesis of (R)-phenyl-1,2-ethanediol from racemic styrene oxide by using bacterial and marine fish epoxide hydrolases.

Biotechnol. Lett. 30(1) , 127-33, (2008)

Enantio-convergent hydrolysis of racemic styrene oxides was achieved to prepare enantiopure (R)-phenyl-1,2-ethanediol by using two recombinant epoxide hydrolases (EHs) of a bacterium, Caulobacter cres...

Efficient one-step production of (S)-1-phenyl-1,2-ethanediol from (R)-enantiomer plus NAD(+)-NADPH in-situ regeneration using engineered Escherichia coli.

Microb. Cell Fact. 11 , 167, (2012)

Candida parapsilosis CCTCC M203011 catalyzes the stereoinversion of (R)-1-phenyl-1,2-ethanediol (PED) through oxidation and reduction. Its NAD(+)-linked (R)-carbonyl reductase (RCR) catalyzes the oxid...