PqsR/LasR-IN-1

Names

[ Name ]:
PqsR/LasR-IN-1

Biological Activity

[Description]:

PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of PqsR and LasR systems in P. aeruginosa. PqsR/LasR-IN-1 also inhibits hERG with the IC50 of 6.77 µM[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Pseudomonas aeruginosa[1]

[References]

[1]. Mohammad Anwar Hossain, et al. Design, synthesis, and evaluation of compounds capable of reducing Pseudomonas aeruginosa virulence. Eur J Med Chem. 2020 Jan 1;185:111800.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₀ClNO₃

[ Molecular Weight ]:
405.87

Related Compounds

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