Propargyl-PEG3-methane
Names
[ CAS No. ]:
89635-82-5
[ Name ]:
Propargyl-PEG3-methane
[Synonym ]:
methoxytriethylenoxy propargyl ether
2,5,8,11-Tetraoxatetradec-13-yne
Biological Activity
[Description]:
Propargyl-PEG3-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C10H18O4
[ Molecular Weight ]:
202.24800
[ Exact Mass ]:
202.12100
[ PSA ]:
36.92000
[ LogP ]:
0.31580