t-Boc-N-amido-PEG5-acetic acid
Names
[ CAS No. ]:
890152-41-7
[ Name ]:
t-Boc-N-amido-PEG5-acetic acid
[Synonym ]:
2,2-Dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-azadocosan-22-oic acid, Boc-NH-PEG5-CH2COOH
Biological Activity
[Description]:
BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C17H33NO9
[ Molecular Weight ]:
395.45