p-Menthone
Names
[ CAS No. ]:
89-80-5
[ Name ]:
p-Menthone
[Synonym ]:
(2R,5S)-5-methyl-2-(propan-2-yl)cyclohexanone
(+/-)-menthone
Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2R,5S)-rel-
(+/-)-3-menthone
CYCLOHEXANONE,5-METHYL-2-(1-METHYLETHYL)-, (2R,5S)-REL-
(2R,5S)-2-Isopropyl-5-methylcyclohexanone
Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2R,5S)-
rel-(2R,5S)-2-isopropyl-5-methylcyclohexanone
Cyclohexanone, 5-methyl-2-(1-methylethyl)-, (2R-trans)-
MENTHONE (REFERENCE GRADE)
p-Menthone
DL-MENTHONE
(2SR,5RS)-5-methyl-2-isopropylcyclohexanone
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
205.0±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C10H18O
[ Molecular Weight ]:
154.249
[ Flash Point ]:
72.8±0.0 °C
[ Exact Mass ]:
154.135757
[ PSA ]:
17.07000
[ LogP ]:
2.63
[ Vapour Pressure ]:
0.3±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.443
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OS9542200
- CHEMICAL NAME :
- p-Menthan-3-one, trans-
- CAS REGISTRY NUMBER :
- 89-80-5
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C10-H18-O
- MOLECULAR WEIGHT :
- 154.28
- WISWESSER LINE NOTATION :
- L6VTJ BY1&1 E1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2180 mg/kg
- TOXIC EFFECTS :
- Behavioral - anticonvulsant Behavioral - sleep
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Cardiac - change in rate Vascular - BP lowering not characterized in autonomic section
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 6400 ng/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 138,17,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0386 No. of Facilities: 18 (estimated) No. of Industries: 1 No. of Occupations: 13 No. of Employees: 3245 (estimated)
Safety Information
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36;R43;R52/53
[ Safety Phrases ]:
S26-S36/37-S61