TA-1801

Names

[ CAS No. ]:
88352-44-7

[ Name ]:
TA-1801

[Synonym ]:
ta 1801
TA-1801

Biological Activity

[Description]:

TA-1801 is a hypolipidemic agent.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vitro]

TA-1801 inhibits platelet aggregation in vitro[1].

[In Vivo]

TA-1801 reduces serum cholesterol and triglyceride levels by 23% and 35%, respectively, at a dose of 0.05% in a diet in normal rats, and it is about 10 times more active in hereditary hyperlipidemic rats (THLR/1) than in normal rats[1].

[References]

[1]. Moriya T, et al. Synthesis of ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxazoleacetate, a hypolipidemic agent, and related compounds. J Med Chem. 1988 Jun;31(6):1197-204.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.275g/cm3

[ Boiling Point ]:
471ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₄ClNO₄

[ Molecular Weight ]:
331.75000

[ Flash Point ]:
238.6ºC

[ Exact Mass ]:
331.06100

[ PSA ]:
65.47000

[ LogP ]:
4.36060

[ Index of Refraction ]:
1.556

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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