88352-44-7

88352-44-7 structure
88352-44-7 structure
  • Name: TA-1801
  • Chemical Name: ethyl 2-[2-(4-chlorophenyl)-5-(furan-2-yl)-1,3-oxazol-4-yl]acetate
  • CAS Number: 88352-44-7
  • Molecular Formula: C17H14ClNO4
  • Molecular Weight: 331.75000
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2017-03-20 13:15:38
  • Modify Date: 2024-01-09 12:48:54
  • TA-1801 is a hypolipidemic agent.

Name ethyl 2-[2-(4-chlorophenyl)-5-(furan-2-yl)-1,3-oxazol-4-yl]acetate
Synonyms ta 1801
TA-1801
Description TA-1801 is a hypolipidemic agent.
Related Catalog
In Vitro TA-1801 inhibits platelet aggregation in vitro[1].
In Vivo TA-1801 reduces serum cholesterol and triglyceride levels by 23% and 35%, respectively, at a dose of 0.05% in a diet in normal rats, and it is about 10 times more active in hereditary hyperlipidemic rats (THLR/1) than in normal rats[1].
References

[1]. Moriya T, et al. Synthesis of ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxazoleacetate, a hypolipidemic agent, and related compounds. J Med Chem. 1988 Jun;31(6):1197-204.

Density 1.275g/cm3
Boiling Point 471ºC at 760 mmHg
Molecular Formula C17H14ClNO4
Molecular Weight 331.75000
Flash Point 238.6ºC
Exact Mass 331.06100
PSA 65.47000
LogP 4.36060
Index of Refraction 1.556
Storage condition 2-8℃
Precursor  3

DownStream  0