SPIPERONE N-METHYL- HCL

Names

[ Name ]:
SPIPERONE N-METHYL- HCL

[Synonym ]:
SPIPERONE N-METHYL- HCL
1,3,8-Triazaspiro(4.5)decan-4-one,8-(4-(4-fluorophenyl)-4-oxobutyl)-3-methyl-1-phenyl
N-methyl-spiperone
Mespiperone
methylspiperone
[3H]methylspiperone
N-Methylspiroperidol
N-Methylspiperone hydrochloride
8-[4-(4-fluorophenyl)-4-oxo-butyl]-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
3-N-Methylspiperone
SPIPERONE N-METHYL- HCL

Chemical & Physical Properties

[ Density]:
1.25g/cm3

[ Boiling Point ]:
608ºC at 760 mmHg

[ Molecular Formula ]:
C₂₄H₂₈FN₃O₂

[ Molecular Weight ]:
409.49600

[ Flash Point ]:
321.5ºC

[ Exact Mass ]:
409.21700

[ PSA ]:
43.86000

[ LogP ]:
3.50010

[ Index of Refraction ]:
1.622

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Dopamine beta-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding.

Synapse 64(9) , 699-703, (2010)

In vitro, D(2) dopamine receptors (DAR) can exist in low- and high-affinity states for agonists and increases of D(2) receptors in high-affinity state have been proposed to underlie DA receptor supers...

Frightening music triggers rapid changes in brain monoamine receptors: a pilot PET study.

J. Nucl. Med. 53(10) , 1573-8, (2012)

Frightening music can rapidly arouse emotions in listeners that mimic those from actual life-threatening experiences. However, studies of the underlying mechanism for perceiving danger created by musi...

Competition between 11C-raclopride and endogenous dopamine in Parkinson's disease.

Nucl. Med. Commun. 31(2) , 159-66, (2010)

The aim of this study was to understand whether the increase in 11C-raclopride binding in the striatum of patients with Parkinson's disease (PD) is associated with the depletion of endogenous dopamine...