PKC-IN-7
Names
[ CAS No. ]:
860468-10-6
[ Name ]:
PKC-IN-7
Biological Activity
[Description]:
PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM; dispalys >50-fold selectivity against PKC isotypes δ,ε,η,θ and other kinases belonging to the AGC family; inhibits IgM-stimulated mouse B cell proliferation with an IC50 of 296 nM.
[References]
References 1. van Eis MJ, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):781-786. View Related Products by Target PKC
Chemical & Physical Properties
[ Molecular Formula ]:
C26H22ClN3O2
[ Molecular Weight ]:
443.931
Related Compounds
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