Boc-NH-PEG4-NHS ester
Names
[ CAS No. ]:
859230-20-9
[ Name ]:
Boc-NH-PEG4-NHS ester
[Synonym ]:
2-Methyl-2-propanyl {15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}carbamate
Carbamic acid, N-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-, 1,1-dimethylethyl ester
Biological Activity
[Description]:
Boc-NH-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Molecular Formula ]:
C20H34N2O10
[ Molecular Weight ]:
462.491
[ Exact Mass ]:
462.221344
[ LogP ]:
-1.66
[ Index of Refraction ]:
1.501