Menthol glucuronide

Names

[ Name ]:
Menthol glucuronide

[Synonym ]:
(1R,2S,5R)-(-)-Menthol β-D-Glucuronide
(1R,2S,5R)-(-)-Menthol Beta-D-Glucuronide

Biological Activity

[Description]:

Menthol glucuronide is a metabolite of Menthol (HY-N1369), and acts as a plasma and urine biomarker of acute Menthol inhalation[1][2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Menthol, a monoterpene, is a principal component of peppermint oil and is used extensively in consumer products as a flavoring aid. Menthol has a half-life of 3-6 h and is rapidly metabolized to menthol glucuronide which is detectable in urine and serum following menthol use[2].

[References]

[1]. Peter Jatlow, et al. Plasma Menthol Glucuronide as a Biomarker of Acute Menthol Inhalation. Tob Regul Sci. 2018 Jan; 4(1): 586–591.

[2]. Judy Peat, et al. Determination of Menthol in Plasma and Urine by Gas Chromatography/Mass Spectrometry (GC/MS). Methods Mol Biol. 2016;1383:205-11.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₈O₇

[ Molecular Weight ]:
332.38900

[ Exact Mass ]:
332.18400

[ PSA ]:
116.45000

[ LogP ]:
0.35600

Precursor & DownStream

Precursor

DownStream

Related Compounds

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