Tetraethylammonium hydroxide

Names

[ CAS No. ]:
77-98-5

[ Name ]:
Tetraethylammonium hydroxide

[Synonym ]:
Ethanaminium, N,N,N-triethyl-, hydroxide (1:1)
Tetraethylammonium hydroxide
tetraethyl-ammoniuhydroxide
Tetraethylammoniumhydroxides
EINECS 201-073-3
Tetraethylazanium hydroxide
TEA HYDROXIDE
Tetraethylammonium h
TENOH
N,N,N-Triethylethanaminium hydroxide
IPC-TEA-OH
MFCD00009024
2K2&2&2 &&OH-

Chemical & Physical Properties

[ Density]:
1.023 g/mL at 25 °C

[ Boiling Point ]:
110 °C

[ Melting Point ]:
-98ºC

[ Molecular Formula ]:
C₈H₂₁NO

[ Molecular Weight ]:
147.258

[ Flash Point ]:
11 °C

[ Exact Mass ]:
147.162308

[ PSA ]:
23.06000

[ LogP ]:
1.70600

[ Index of Refraction ]:
n20/D 1.422

[ Stability ]:
Stable, but absorbs carbon dioxide from the air

[ Water Solubility ]:
SOLUBLE

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KH3150000

CHEMICAL NAME :: Ethanaminium, N,N,N-triethyl-, hydroxide

CAS REGISTRY NUMBER :: 77-98-5

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C8-H20-N.H-O

MOLECULAR WEIGHT :: 147.30

WISWESSER LINE NOTATION :: 2K2&2&2 &Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 107 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 28,367,1926

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,681,1948 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4954 No. of Facilities: 6 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 215 (estimated) No. of Female Employees: 168 (estimated)

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11;R23/24/25;R34;R39/23/24/25;R51

[ Safety Phrases ]:
S7-S16-S26-S36/37/39-S45-S61

[ RIDADR ]:
UN 3286 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
KH3150000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2923900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Extracellular quaternary ammonium blockade of transient receptor potential vanilloid subtype 1 channels expressed in Xenopus laevis oocytes.

Mol. Pharmacol. 82(6) , 1129-35, (2012)

Transient receptor potential vanilloid subtype 1 (TRPV1) channels are essential nociceptive integrators in primary afferent neurons. These nonselective cation channels are inhibited by local anestheti...

Remarkably regioselective deacylation of cellulose esters using tetraalkylammonium salts of the strongly basic hydroxide ion.

Carbohydr. Polym. 111 , 25-32, (2014)

Tetraalkylammonium hydroxides have been found to mediate regioselective deacylation of cellulose esters. This deacylation surprisingly shows substantial selectivity for the removal of the acyl groups ...

Use of ion-pairing reagent for improving iodine speciation analysis in seaweed by pressure-driven capillary electrophoresis and ultraviolet detection.

J. Chromatogr. A. 1379 , 112-7, (2015)

This study achieved resolution improvement for iodine speciation in the presence of an ion-pairing reagent by a pressure-driven capillary electrophoresis (CE) system. Addition of 0.01mM tetrabutyl amm...