beta-Estradiol 17-hemisuccinate
Names
[ CAS No. ]:
7698-93-3
[ Name ]:
beta-Estradiol 17-hemisuccinate
[Synonym ]:
17beta-Estradiol hemisuccinate
1,3,5(10)-Estratriene-3,17beta-diol 17-hemisuccinate
4-{[(14beta,17alpha)-3-Hydroxyestra-1,3,5(10)-Trien-17-Yl]oxy}-4-Oxobutanoic Acid
Eutocol (TN)
4-{[(17β)-3-Hydroxyestra-1,3,5(10)-trien-17-yl]oxy}-4-oxobutanoic acid
17BETA-ESTRADIOL 17-HEMISUCCINATE
Estradiol-17-hemisuccinate
Butanedioic acid, mono[(17β)-3-hydroxyestra-1,3,5(10)-trien-17-yl] ester
beta-Estradiol 17-hemisuccinate
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
570.1±50.0 °C at 760 mmHg
[ Melting Point ]:
162-164°C (lit.)
[ Molecular Formula ]:
C22H28O5
[ Molecular Weight ]:
372.455
[ Flash Point ]:
198.7±23.6 °C
[ Exact Mass ]:
372.193665
[ PSA ]:
83.83000
[ LogP ]:
4.64
[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C
[ Index of Refraction ]:
1.598
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H332-H351
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
20/21/22-40
[ Safety Phrases ]:
22-36
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Neuroimmunol. , (2008)
Estrogen has been shown to attenuate the inflammatory response following injury or lipopolysaccharide treatment in several organ systems. Estrogen's actions are transduced through two estrogen recepto...
Steroid-bovine serum albumin conjugates: molecular characterization and their interaction with androgen and estrogen receptors.J. Steroid Biochem. 24(5) , 1017-31, (1986)
Conjugates of testosterone-3-carboxymethyloxime (T-3-CMO), testosterone-17-hemisuccinate (T-17-HS), 17 beta-estradiol-6-carboxymethyloxime (E-6-CMO), or 17 beta-estradiol-17-hemisuccinate (E-17-HS) an...
Prevention of bridge binding in immunoassays: a general estradiol tracer structure.J. Steroid Biochem. 32(2) , 251-7, (1989)
Iodinated estradiol tracers were synthesized with three different bridges connecting the radiolabelled moiety to the steroid core: Hemisuccinate, carboxymethyloxime and amide. Taking these iodinated t...