2',4',7-trihydroxyisoflavone

Names

[ Name ]:
2',4',7-trihydroxyisoflavone

[Synonym ]:
2',4',7-trihydroxyisoflavone
4H-1-Benzopyran-4-one, 3-(2,4-dihydroxyphenyl)-7-hydroxy-
3-(2,4-dihydroxyphenyl)-7-hydroxychromen-4-one
3-(2,4-Dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one
7,2',4'-trihydroxyisoflavone
2'-hydroxyformononetin

Biological Activity

[Description]:

2′-Hydroxydaidzein is a metabolite. 2′-Hydroxydaidzein inhibits the release of chemical mediator from inflammatory cells. 2′-Hydroxydaidzein significantly inhibits lysozyme and β-glucuronidase release from rat neutrophils, which is stimulated with fMLP/CB, respectively[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Ko HH, et al. Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. Bioorg Med Chem Lett. 2004 Feb 23;14(4):1011-4.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
575.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₀O₅

[ Molecular Weight ]:
270.24

[ Flash Point ]:
225.2±23.6 °C

[ Exact Mass ]:
270.052826

[ PSA ]:
90.90000

[ LogP ]:
2.81

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.732

2',4',7-trihydroxyisoflavone

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds