2',4',7-trihydroxyisoflavone

Modify Date: 2025-08-26 20:13:45

2',4',7-trihydroxyisoflavone Structure
2',4',7-trihydroxyisoflavone structure
Common Name 2',4',7-trihydroxyisoflavone
CAS Number 7678-85-5 Molecular Weight 270.24
Density 1.5±0.1 g/cm3 Boiling Point 575.7±50.0 °C at 760 mmHg
Molecular Formula C15H10O5 Melting Point N/A
MSDS N/A Flash Point 225.2±23.6 °C

 Use of 2',4',7-trihydroxyisoflavone


2′-Hydroxydaidzein is a metabolite. 2′-Hydroxydaidzein inhibits the release of chemical mediator from inflammatory cells. 2′-Hydroxydaidzein significantly inhibits lysozyme and β-glucuronidase release from rat neutrophils, which is stimulated with fMLP/CB, respectively[1].

 Names

Name 2'-hydroxydaidzein
Synonym More Synonyms

 2',4',7-trihydroxyisoflavone Biological Activity

Description 2′-Hydroxydaidzein is a metabolite. 2′-Hydroxydaidzein inhibits the release of chemical mediator from inflammatory cells. 2′-Hydroxydaidzein significantly inhibits lysozyme and β-glucuronidase release from rat neutrophils, which is stimulated with fMLP/CB, respectively[1].
Related Catalog
References

[1]. Ko HH, et al. Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. Bioorg Med Chem Lett. 2004 Feb 23;14(4):1011-4.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 575.7±50.0 °C at 760 mmHg
Molecular Formula C15H10O5
Molecular Weight 270.24
Flash Point 225.2±23.6 °C
Exact Mass 270.052826
PSA 90.90000
LogP 2.81
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.732
InChIKey ZCTNPCRBEWXCGP-UHFFFAOYSA-N
SMILES O=c1c(-c2ccc(O)cc2O)coc2cc(O)ccc12

 Synthetic Route

~61%

2',4',7-trihydroxyisoflavone Structure

2',4',7-trihydr...

CAS#:7678-85-5

Literature: Woodward, Michael D. Phytochemistry (Elsevier), 1980 , vol. 19, p. 921 - 928

~%

2',4',7-trihydroxyisoflavone Structure

2',4',7-trihydr...

CAS#:7678-85-5

Literature: Visser, Frans R.; Lane, Geoffrey A. Australian Journal of Chemistry, 1987 , vol. 40, # 10 p. 1705 - 1711

~%

2',4',7-trihydroxyisoflavone Structure

2',4',7-trihydr...

CAS#:7678-85-5

Literature: Wyeth Patent: US2003/87955 A1, 2003 ; US 20030087955 A1

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

2',4',7-trihydroxyisoflavone
4H-1-Benzopyran-4-one, 3-(2,4-dihydroxyphenyl)-7-hydroxy-
3-(2,4-dihydroxyphenyl)-7-hydroxychromen-4-one
3-(2,4-Dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one
7,2',4'-trihydroxyisoflavone
2'-hydroxyformononetin
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