Trichloroacetyl chloride

Names

[ CAS No. ]:
76-02-8

[ Name ]:
Trichloroacetyl chloride

[Synonym ]:
Trichloroacetochloride
Acetyl chloride, 2,2,2-trichloro-
Acetyl chloride, trichloro-
CCl3COCl
EINECS 200-926-7
TRICHLOROACETIC ACID CHLORIDE
Trichloroacetyl chloride [UN2442] [Corrosive]
MFCD00000792
Trichloroacetyl chloride
2,2,2-Trichloroethanoyl chloride

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
118.0±0.0 °C at 760 mmHg

[ Melting Point ]:
-57 °C

[ Molecular Formula ]:
C₂Cl₄O

[ Molecular Weight ]:
181.833

[ Flash Point ]:
31.0±26.5 °C

[ Exact Mass ]:
179.870331

[ PSA ]:
17.07000

[ LogP ]:
2.39

[ Vapour Pressure ]:
17.0±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.501

[ Stability ]:
Stable. Reacts violently with water. Incompatible with alcohols, oxidizing agents, strong bases.

[ Water Solubility ]:
reacts violently

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AO7140000

CHEMICAL NAME :: Acetyl chloride, trichloro-

CAS REGISTRY NUMBER :: 76-02-8

BEILSTEIN REFERENCE NO. :: 0774120

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C2-Cl4-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,113,1982

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 475 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,113,1982

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 445 mg/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,113,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7270 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314-H330

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P260-P280-P284-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T+:Verytoxic;

[ Risk Phrases ]:
R14;R22;R26;R29;R35

[ Safety Phrases ]:
S26-S28-S36/37/39-S45-S8-S28A-S23

[ RIDADR ]:
UN 2442 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
AO7140000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

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The first examples of dihydro-1H-benzindoles by enantioselective γ-lactamization reaction of naphthyl sulfilimines with trichloroacetyl chloride in the presence of ZnCu as catalyst (≥98:2 er and 65-80...

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