3,3',4,4'-Biphenyltetramine tetrahydrochloride
Names
[ CAS No. ]:
7411-49-6
[ Name ]:
3,3',4,4'-Biphenyltetramine tetrahydrochloride
[Synonym ]:
DAB TABLET
DAB SUBSTRATE
DAB-HCL
Biphenyl-3,3',4,4'-tetramine tetrahydrochloride
DAB TETRAHYDROCHLORIDE
DAB
3,3',4,4'-Biphenyltetramine tetrahydrochloride
DAB,tetrahydrochloride3
3,3`-Diaminobenzidine tetrahydrochloride
DAB EASY tablets
DAB anhydrous
MFCD00012969
[1,1'-Biphenyl]-3,3',4,4'-tetramine, hydrochloride (1:4)
DAB 4HCL
EINECS 231-018-9
DAB WITH METAL ENHANCER
Biological Activity
[Description]:
[Related Catalog]:
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Boiling Point ]:
481.7ºC at 760 mmHg
[ Melting Point ]:
300°C
[ Molecular Formula ]:
C12H18Cl4N4
[ Molecular Weight ]:
360.110
[ Flash Point ]:
282.7ºC
[ Exact Mass ]:
358.028564
[ PSA ]:
104.08000
[ LogP ]:
7.21520
[ Water Solubility ]:
Soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DV8753000
- CHEMICAL NAME :
- 3,3',4,4'-Biphenyltetramine, tetrahydrochloride
- CAS REGISTRY NUMBER :
- 7411-49-6
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C12-H14-N4.4Cl-H
- MOLECULAR WEIGHT :
- 360.14
- WISWESSER LINE NOTATION :
- ZR BZ DR CZ DZ &GH 4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 330 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCIBR* Progress Report for Contract No. NIH-NCI-E-68-1311, Submitted to the National Cancer Institute by Bio-Research Consultants, Inc. (9 Commercial Ave., Cambridge, MA 02141) Volume(issue)/page/year: NCI-E-68-1311,1973 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 260 gm/kg/78W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
- REFERENCE :
- JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 2(2),325,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 260 gm/kg/78W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 2(2),325,1978
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 520 gm/kg/78W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 2(2),325,1978
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H319-H341-H350
[ Precautionary Statements ]:
P201-P280-P301 + P312 + P330-P305 + P351 + P338-P308 + P313-P337 + P313
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38;R40
[ Safety Phrases ]:
S7-S16-S24-S33-S36/37-S45-S24/25-S22
[ RIDADR ]:
UN 3316 9/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
DV8753000
[ Hazard Class ]:
9.0
Articles
Bull. Environ. Contam. Toxicol. 87(3) , 226-30, (2011)
The objective of this study was to examine the influence of different stressors, including cadmium (heavy metal), anthracene (polycyclic aromatic hydrocarbon-PAH) and chloridazon (herbicide), on popul...
The bioanalysis of trastuzumab in human serum using precipitate-enhanced ellipsometry.Anal. Biochem. 393 , 73-79, (2009)
For the bioanalysis of therapeutic monoclonal antibodies in biological matrices, immunoassays--especially enzyme-linked immunosorbent assays (ELISAs)--are the most widely used techniques. Although ELI...
Color modification of diaminobenzidine (DAB) precipitation by metallic ions and its application for double immunohistochemistry.J. Histochem. Cytochem. 30 , 1079-1082, (1982)
Three metallic ions, NiCl2, CoCl2, and CuSO4, were found to modify the color of the normally brown diaminobenzidine (DAB) reaction. The colors ranged from purplish blue (NiCl2), dark blue/bluish black...