(R)-Mephenytoin
Names
Biological Activity
[Description]:
(R)-Mephenytoin ((-)-Mephenytoin), the R-enantiomer of Mephenytoin. Mephenytoin is an Anticonvulsant agent[1][2].
[Related Catalog]:
[In Vitro]
(R)-Mephenytoin can be N-demethylated by the cytochrome P450 (CYP) isoform CYP2C9 to form the metabolite 5-phenyl-5-ethylhydantoin (nirvanol)[1].
[References]
Chemical & Physical Properties
[ Density]:
1.154g/cm3
[ Melting Point ]:
137-138ºC
[ Molecular Formula ]:
C12H14N2O2
[ Molecular Weight ]:
218.25200
[ Exact Mass ]:
218.10600
[ PSA ]:
49.41000
[ LogP ]:
1.74020
[ Index of Refraction ]:
1.541
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
22-36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
NONH for all modes of transport