Melevodopa
Names
[ CAS No. ]:
7101-51-1
[ Name ]:
Melevodopa
[Synonym ]:
3-Hydroxy-L-tyrosine methyl ester
(S)-(-)-methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate
(S)-2-Amino-3-(3,4-dihydroxy-phenyl
3,4-dihydroxy-L-phenylalanine methyl ester
L-Dopa methyl ester
Levodopa methyl ester
Melevodopa (INN)
methyl-L-DOPA
Melevodopa
(2S)-2-amino-3-(3,4-dihydroxy-phenyl)-propionic acid methyl ester
Chemical & Physical Properties
[ Density]:
1.322g/cm3
[ Boiling Point ]:
384.4ºC at 760 mmHg
[ Molecular Formula ]:
C10H13NO4
[ Molecular Weight ]:
211.21500
[ Flash Point ]:
186.3ºC
[ Exact Mass ]:
211.08400
[ PSA ]:
92.78000
[ LogP ]:
0.84090
[ Index of Refraction ]:
1.592
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AY5960000
- CHEMICAL NAME :
- Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, L-
- CAS REGISTRY NUMBER :
- 7101-51-1
- BEILSTEIN REFERENCE NO. :
- 3056415
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C10-H13-N-O4
- MOLECULAR WEIGHT :
- 211.24
- WISWESSER LINE NOTATION :
- QR BQ D1YZVO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Cells - not otherwise specified
- DOSE/DURATION :
- 3300 nmol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,1414,1980
Safety Information
[ Hazard Codes ]:
Xn
[ HS Code ]:
2922509090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922509090
[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%