1-Fluoro-2,4-dinitrobenzene

Names

[ CAS No. ]:
70-34-8

[ Name ]:
1-Fluoro-2,4-dinitrobenzene

[Synonym ]:
Sanger reagent
Sanger's Reagent
2,4-DNBF
2,4-Dinitrofluorobenzene
DNFB
fluoro-2,4-dinitrobenzene
Dinitrofluorobenzene
EINECS 200-734-3
Fluorodinitrobenzene
Benzene, 1-fluoro-2,4-dinitro-
FDNB
MFCD00007056
Benzene,1-fluoro-2,4-dinitro
2,4-dinitro-fluoro-benzene
2,4-Dinitro-1-fluorobenzene

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
296.0±20.0 °C at 760 mmHg

[ Melting Point ]:
25-27 °C(lit.)

[ Molecular Formula ]:
C₆H₃FN₂O₄

[ Molecular Weight ]:
186.097

[ Flash Point ]:
132.8±21.8 °C

[ Exact Mass ]:
186.007690

[ PSA ]:
91.64000

[ LogP ]:
1.16

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.585

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.

[ Water Solubility ]:
400 mg/L (25 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ7800000

CHEMICAL NAME :: Benzene, 2,4-dinitro-1-fluoro-

CAS REGISTRY NUMBER :: 70-34-8

BEILSTEIN REFERENCE NO. :: 0398632

LAST UPDATED :: 199710

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C6-H3-F-N2-O4

MOLECULAR WEIGHT :: 186.11

WISWESSER LINE NOTATION :: WNR BF ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - hamster Kidney

DOSE/DURATION :: 80 ug/L

REFERENCE :: BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 37,873,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5163 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H317-H319-H335-H373

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R22;R23/24/25;R33;R34;R40;R42/43

[ Safety Phrases ]:
S22-S26-S36/37/39-S45-S28A

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
CZ7800000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29049085

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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