(2S,3R,4E)-2-Amino-4-heptadecene-1,3-diol

Names

[ Name ]:
(2S,3R,4E)-2-Amino-4-heptadecene-1,3-diol

[Synonym ]:
C17-Sphingosine
(2S,3R,4E)-2-Amino-4-heptadecene-1,3-diol
4-Heptadecene-1,3-diol, 2-amino-, (2S,3R,4E)-
D-erythro-Heptadephing-4-enine

Biological Activity

[Description]:

Sphingosine (d17:1) is a 17-carbon sphingosine found in human skin. Sphingosine (d17:1) can be phosphorylated by sphingosine kinases to produce C-17 sphingosine-1-phosphate. Sphingosine C-17 was used as an internal standard for spectral analysis of sphingoid compounds[1][2][3].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Stewart ME, et al. Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines. J Invest Dermatol. 1995 Oct;105(4):613-8.

[2]. Hong JH, et al. K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling. J Invest Dermatol. 2008 Sep;128(9):2166-78.

[3]. Choi CH, et al. Sphingosine 1-phosphate and sphingosine kinase activity during chicken embryonic development. Arch Pharm Res. 2007 Apr;30(4):502-6.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
432.9±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₃₅NO₂

[ Molecular Weight ]:
285.47

[ Flash Point ]:
215.6±28.7 °C

[ Exact Mass ]:
285.266785

[ PSA ]:
66.48000

[ LogP ]:
5.87

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.490

[ Storage condition ]:
-20°C

Safety Information

[ HS Code ]:
2922199090

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%