Sphingosine (d12:1)

Names

[ Name ]:
Sphingosine (d12:1)

[Synonym ]:
D-erythro-sphingosine
C12-Sphingosine

Biological Activity

[Description]:

C12-Sphingosine is a short-chain Sphingosine homologue. C12-Sphingosine inhibits serine palmitoyltransferase activity in primary cultured cerebellar cells[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

C12-Sphingosine inhibits dr novo sphingosine and sphingolipid biosynthesis in murine cerebellar cells. C12-Sphingosine decreases serine palrnitoyltransferase activity in primary cultured neurons in a time- and concentration-dependent manner[1].

[References]

[1]. E C Mandon, et al. Sphingolipid biosynthesis in cultured neurons. Down-regulation of serine palmitoyltransferase by sphingoid bases. Eur J Biochem. 1991 Jun 15;198(3):667-74.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₂₅NO₂

[ Molecular Weight ]:
215.33200

[ Exact Mass ]:
215.18900

[ PSA ]:
66.48000

[ LogP ]:
2.28390

Related Compounds

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