<Suppliers Price>

m-PEG3-CH2CH2COOH

Names

[ CAS No. ]:
67319-28-2

[ Name ]:
m-PEG3-CH2CH2COOH

[Synonym ]:
2,5,8,11-Tetraoxatetradecan-14-oic acid
MFCD11041124

Biological Activity

[Description]:

m-PEG3-CH2CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Robert Lyon, et al. Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics. WO2015057699A2.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
352.3±32.0 °C at 760 mmHg

[ Molecular Formula ]:
C10H20O6

[ Molecular Weight ]:
236.262

[ Flash Point ]:
129.8±18.6 °C

[ Exact Mass ]:
236.125992

[ LogP ]:
-1.35

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.445


Related Compounds