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IU1-47

Names

[ CAS No. ]:
670270-31-2

[ Name ]:
IU1-47

Biological Activity

[Description]:

IU1-47 is a potent USP14 inhibitor with an IC50 of 0.6 μM. IU1-47 induces tau elimination in cultured neurons[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase
Research Areas >> Neurological Disease

[References]

[1]. Boselli M, et al. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. J Biol Chem. 2017 Nov 24;292(47):19209-19225.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H23ClN2O

[ Molecular Weight ]:
330.85

[ Storage condition ]:
2-8℃

Related Compounds