Mycobactin-IN-1

Names

[ Name ]:
Mycobactin-IN-1

Biological Activity

[Description]:

Mycobactin-IN-1 (compound 44), a pyrazoline analogue, is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-1 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Mousumi Shyam，et al. Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition.J Med Chem. 2022 Jan 13;65(1):234-256.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₃ClN₂O

[ Molecular Weight ]:
272.73

Related Compounds

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