Azide-C2-Azide

Names

[ CAS No. ]:
629-13-0

[ Name ]:
Azide-C2-Azide

[Synonym ]:
Aethylendiazid
Ethane,1,2-diazido
1,2-Diazido-aethan
1,2-diazido-ethane
1.2-Diazo-aethan
Aethylenazid

Biological Activity

[Description]:

Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂H₄N₆

[ Molecular Weight ]:
112.09300

[ Exact Mass ]:
112.05000

[ PSA ]:
99.50000

[ LogP ]:
0.51252

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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