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(5ξ,9ξ,13α)-Pimara-7,15-dien-18-oic acid

Names

[ CAS No. ]:
5835-26-7

[ Name ]:
(5ξ,9ξ,13α)-Pimara-7,15-dien-18-oic acid

[Synonym ]:
IsopiMaric acid
(5ξ,9ξ,13α)-Pimara-7,15-dien-18-oic acid
1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-trimethyl-, (1R,4aR,7S)-
7,15-Isopimaradien-18-oic acid
Isopimarsaeure

Biological Activity

[Description]:

Isopimaric acid is a potent opener of large conductance calcium activated K+ (BK) channels.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
416.7±45.0 °C at 760 mmHg

[ Melting Point ]:
160°

[ Molecular Formula ]:
C20H30O2

[ Molecular Weight ]:
302.451

[ Flash Point ]:
200.0±23.4 °C

[ Exact Mass ]:
302.224579

[ PSA ]:
37.30000

[ LogP ]:
6.61

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.538

MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
N

[ RIDADR ]:
UN 3077 9 / PGIII

[ WGK Germany ]:
3

Precursor & DownStream

Articles

Phloroglucinols from anti-microbial deposit-resins of Australian stingless bees (Tetragonula carbonaria).

Phytother Res. 29(1) , 48-58, (2015)

Stingless bees accumulate deposits of plant resins that are mixed with beeswax to produce propolis. Previous studies have reported anti-microbial constituents of stingless bee (Tetragonula carbonaria)...

Spontaneous and evoked contractions are regulated by PKC-mediated signaling in detrusor smooth muscle: involvement of BK channels.

Am. J. Physiol. Renal Physiol. 304(5) , F451-62, (2013)

Protein kinase C (PKC) and large conductance Ca(2+)-activated potassium channels (BK) are downregulated in the detrusor smooth muscle (DSM) in partial bladder outlet obstruction (PBOO). DSM from these...

[Analysis of main chemical composition in hydrogenated rosin from Zhuzhou].

Se Pu 19(1) , 78-81, (2001)

The acid fraction, the main part of the hydrogenated rosin produced by Zhuzhou Forest Chemicals Plant of China, was separated from neutral fraction by modified DEAE-Sephadex ion exchange chromatograph...


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Related Compounds