neo-Abietic acid

Names

[ CAS No. ]:
471-77-2

[ Name ]:
neo-Abietic acid

[Synonym ]:
8(14),13(15)-Abietadien-18-oic acid
[1theta-(1alpha,4abeta,4balpha,10aalpha)]-methyl-7-(1-methylethylidene)
Abieta-8(14),13(15)-dien-18-oic acid
Podocarp-8(14)-en-15-oic acid, 13-isopropylidene-
neo-Abietic acid
NEOABIETIC ACID,STANDARD FOR GC
Abieta-8(14),13(15)-dien-18-saeure
13-Isopropylidenepodocarp-8(14)-en-18-oic acid
13-isopropylidene-podocarp-8(14)-en-15-oicaci
1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a-dimethyl-7-(1-methylethylidene)-, (1R,4aR,4bS,10aR)-
Podocarp-8(14)-en-15-oic acid,13-isopropylidene
CTCM 189
Abietadien-(8(14).13(15))-saeure-(18)
Neoabietinsaeure
Neoabietsaeure

Biological Activity

[Description]:

Neoabietic acid is an abietic-type acid isolated from the oleoresin and rosin of Pinus palustris. Neoabietic acid is highly susceptible to mineral acid. Neoabietic acid has antibacterial activity in vitro[1][2][3].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. HARRIS GC, et, al. Resin acids; an improved method of isolation of resin acids the isolation of a new abietic-type acid, neoabietic acid. J Am Chem Soc. 1948 Jan; 70(1): 334-9.

[2]. Jagalski V, et, al. Biophysical study of resin acid effects on phospholipid membrane structure and properties. Biochim Biophys Acta. 2016 Nov; 1858(11):2827-2838.

[3]. Söderberg TA, et, al. Antibacterial activity of rosin and resin acids in vitro. Scand J Plast Reconstr Surg Hand Surg. 1990; 24(3): 199-205.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
433.4±44.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₀O₂

[ Molecular Weight ]:
302.451

[ Flash Point ]:
206.0±23.1 °C

[ Exact Mass ]:
302.224579

[ PSA ]:
37.30000

[ LogP ]:
6.67

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.542

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TP8740000

CHEMICAL NAME :: Podocarp-8(14)-en-15-oic acid, 13-isopropylidene-

CAS REGISTRY NUMBER :: 471-77-2

BEILSTEIN REFERENCE NO. :: 2702391

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C20-H30-O2

MOLECULAR WEIGHT :: 302.50

WISWESSER LINE NOTATION :: L B666 EY FUTJ A1 EUY1&1 KVQ K1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Yeast - Schizosaccharomyces pombe

DOSE/DURATION :: 90 nmol/L

REFERENCE :: CNJGA8 Canadian Journal of Genetics and Cytology. (National Research Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.1- 1959- Volume(issue)/page/year: 24,771,1982

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ WGK Germany ]:
3

[ RTECS ]:
TP8740000

Precursor & DownStream

Precursor

DownStream

Related Compounds

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