Chinese gallotannin

Names

[ Name ]:
Chinese gallotannin

[Synonym ]:
Quebracho extract
DSSTox_CID_6076
gallotannin
Gallotannic acid
penta-m-digalloyl-glucose
gallotanine
Tanninum
decagalloyl glucose

Biological Activity

[Description]:

Chinese gallotannin is a non-specific promiscuous α-amylase inhibitor with a Ki of 0.82 μg/mL for human salivary α-amylase. Chinese gallotannin can be used for the research of diabetes[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[Target]

Ki: 0.82 μg/mL (Human Salivary α-Amylase)[1] IC50: 2.3 μg/mL (Porcine Pancreatic α-Amylase), 128.9 nM (Telomerase), 3.0 μM (Fatty acid synthase), 6.9 μM (α-Ketoglutarate-Dependent Dioxygenase AlkB), 7.8 μM (5α-Reductase), 24.2 μM (Poly(ADP-ribose) Glycohydrolase)[1]

[References]

[1]. Szabó K, et al. Gallotannins are non-specific inhibitors of α-amylase: Aggregates are the active species taking part in inhibition. Chem Biol Drug Des. 2021 Feb;97(2):349-357.

Chemical & Physical Properties

[ Density]:
2.12 g/cm3

[ Boiling Point ]:
198ºC

[ Melting Point ]:
218ºC(lit.)

[ Molecular Formula ]:
C₇₆H₅₂O₄₆

[ Molecular Weight ]:
1701.20

[ Flash Point ]:
198 °C

[ Exact Mass ]:
1700.17000

[ PSA ]:
777.98000

[ LogP ]:
4.83810

[ Index of Refraction ]:
1.927

Safety Information

[ Safety Phrases ]:
24/25

[ WGK Germany ]:
2

[ RTECS ]:
WW5075000

[ HS Code ]:
3201909000

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 3201909000