L-(+)-Ribulose

Names

[ CAS No. ]:
527-50-4

[ Name ]:
L-(+)-Ribulose

[Synonym ]:
L-Xylulose - Aqueous solution
D-threo-2-Pentulofuranose
L-Ribulose
L-Riboketose
Lg-tartaric acid bis-pentylamide
L-erythro-2-Pentulose
Xylulofuranose
L-erythro-Pentulose
Ribulose
L-Arabinoketose
2,3-Dihydroxy-N~1~,N~4~-dipentylsuccinamide
Xylulose
Lg-Weinsaeure-bis-pentylamid
D-Xylulose
D-threo-2-pentulose
N,N'-dipentyl-L-tartaramide
L-Xylulose
Lg-threo-1,3,4,5-Tetrahydroxy-pentan-2-on
L-Arabinulose

Biological Activity

[Description]:

L-Xylulose is an endogenous metabolite present in Blood, Cerebrospinal_Fluid and Urine that can be used for the research of Ribose 5 Phosphate Isomerase Deficiency[1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

[Target]

Human Endogenous Metabolite

[In Vitro]

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

[References]

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.

[2]. Huck JH, et al. Ribose-5-phosphate isomerase deficiency: new inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy. Am J Hum Genet. 2004 Apr;74(4):745-51.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
364.2±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅H₁₀O₅

[ Molecular Weight ]:
150.130

[ Flash Point ]:
174.1±27.9 °C

[ Exact Mass ]:
150.052826

[ PSA ]:
90.15000

[ LogP ]:
-0.78

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.624

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ HS Code ]:
2914400090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Construction and co-expression of plasmid encoding xylitol dehydrogenase and a cofactor regeneration enzyme for the production of xylitol from D-arabitol.

Enzyme Microb. Technol. 51(2) , 119-24, (2012)

The biotransformation of D-arabitol into xylitol was investigated with focus on the conversion of D-xylulose into xylitol. This critical conversion was accomplished using Escherichia coli to co-expres...

Cloning and characterization of a novel NAD+ -dependent xylitol dehydrogenase from Gluconobacter oxydans CGMCC 1. 637.

Wei Sheng Wu Xue Bao 52(6) , 726-35, (2012)

To clone the xylitol dehydrogenase gene from Gluconobacter oxydans CGMCC 1.637, to characterize enigmatic properties of xylitol dehydrogenase and to investigate the induction abilities of various carb...

Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production.

Biosci. Biotechnol. Biochem. 77(3) , 511-5, (2013)

A gene encoding L-ribulose 3-epimerase (L-RE) from Mesorhizobium loti, an important enzyme for rare sugar production by the Izumoring strategy, was cloned and overexpressed. The enzyme showed highest ...