Prostaglandin G2

Names

[ CAS No. ]:
51982-36-6

[ Name ]:
Prostaglandin G2

[Synonym ]:
Prostaglandin G2
(5Z)-7-{(1R,4S,5R,6R)-6-[(1E,3S)-3-Hydroperoxy-1-octen-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl}-5-heptenoic acid
5-Heptenoic acid, 7-[(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroperoxy-1-octen-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl]-, (5Z)-
MFCD00036971

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
517.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₂O₆

[ Molecular Weight ]:
368.465

[ Flash Point ]:
175.5±23.6 °C

[ Exact Mass ]:
368.219879

[ PSA ]:
85.22000

[ LogP ]:
4.39

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.545

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H319-H336

[ Supplemental HS ]:
Repeated exposure may cause skin dryness or cracking.

[ Precautionary Statements ]:
P210-P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313-P403 + P235

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F: Flammable;Xi: Irritant;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
9-16-26

[ RIDADR ]:
UN 1090 3

Precursor & DownStream

Precursor

DownStream

Articles

The cyclooxygenase reaction mechanism.

Biochemistry 41(52) , 15451-8, (2002)

Endotoxin priming of thromboxane-related vasoconstrictor responses in perfused rabbit lungs.

J. Appl. Physiol. 83(1) , 18-24, (1997)

In prior studies of perfused lungs, endotoxin priming markedly enhanced thromboxane (Tx) generation and Tx-mediated vasoconstriction in response to secondarily applied bacterial exotoxins. The present...

Comparison of peroxidase reaction mechanisms of prostaglandin H synthase-1 containing heme and mangano protoporphyrin IX.

J. Biol. Chem. 272(14) , 8885-94, (1997)

Prostaglandin H synthase (PGHS) is a heme protein that catalyzes both the cyclooxygenase and peroxidase reactions needed to produce prostaglandins G2 and H2 from arachidonic acid. Replacement of the h...