Tarenflurbil
Names
[ CAS No. ]:
51543-40-9
[ Name ]:
Tarenflurbil
[Synonym ]:
R-Flurbiprofen
R-(-)-Flurbiprofen
EINECS 257-264-7
MPC-7869
(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid
UNII-501W00OOWA
(-)-Flurbiprofen
(R)-Flurbiprofen
(2R)-2-(2-Fluoro-1,1'-biphenyl-4-yl)propanoic acid
Flurizan
(R)-2-Flubiprofen
(R)-(−)-2-Fluoro-α-methyl-4-biphenylacetic acid
(2R)-2-(2-Fluoro-4-biphenylyl)propanoic acid
(R)-2-Flurbiprofen
(2R)-2-(3-fluoro-4-phenylphenyl)propanoic acid
[1,1'-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, (αR)-
(R)-(-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid
tarenflurbil
MFCD00869714
E-7869
Flurbiprofen
Biological Activity
[Description]:
[Related Catalog]:
[Target]
IC50: 75 μM (RXRα)[1]
[In Vitro]
[In Vivo]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
376.2±30.0 °C at 760 mmHg
[ Melting Point ]:
110-113ºC
[ Molecular Formula ]:
C15H13FO2
[ Molecular Weight ]:
244.261
[ Flash Point ]:
181.3±24.6 °C
[ Exact Mass ]:
244.089951
[ PSA ]:
37.30000
[ LogP ]:
4.11
[ Appearance of Characters ]:
Crystalline Powder | White to off-white
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.568
MSDS
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301
[ Precautionary Statements ]:
P301 + P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R25
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 2811
[ WGK Germany ]:
3
[ HS Code ]:
2916399090
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Science 453 , 925, (2008)
Selective lowering of Abeta42 levels (the 42-residue isoform of the amyloid-beta peptide) with small-molecule gamma-secretase modulators (GSMs), such as some non-steroidal anti-inflammatory drugs, is ...
Christensen, D.D.J. Clin. Psychiatry 9 , 32, (2007)