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Polyphyllin B

Names

[ CAS No. ]:
50773-42-7

[ Name ]:
Polyphyllin B

[Synonym ]:
formosanin C
Spirost-5-en-3-yl 6-deoxyhexopyranosyl-(1->2)-[6-deoxyhexopyranosyl-(1->4)-6-deoxyhexopyranosyl-(1->4)]hexopyranoside
Polyphyllin B (ForMosanin C)
PolyphyllinB
Hexopyranoside, spirost-5-en-3-yl O--6-deoxyhexopyranosyl-(1->2)-O-[O--6-deoxyhexopyranosyl-(1->4)-6-deoxyhexopyranosyl-(1->4)]-
Parissaponin Pb
Paris II
Parrisaponin
Asperin
Paris saponin II
Polyphyllin II

Biological Activity

[Description]:

Formosanin C is a diosgenin saponin isolated from Paris formosana Hayata and an immunomodulator with antitumor activity. Formosanin C induces apoptosis[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. Wu RT, et al. Formosanin-C, an immunomodulator with antitumor activity. Int J Immunopharmacol. 1990;12(7):777-86.

[2]. Li Y, et al. The antitumor effect of formosanin C on HepG2 cell as revealed by 1H-NMR based metabolic profiling. Chem Biol Interact. 2014 Sep 5;220:193-9.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C51H82O20

[ Molecular Weight ]:
1015.185

[ Exact Mass ]:
1014.539917

[ PSA ]:
294.60000

[ LogP ]:
5.72

[ Index of Refraction ]:
1.621

[ Storage condition ]:
-20°C

Related Compounds