PknB-IN-2

Names

[ CAS No. ]:
500015-22-5

[ Name ]:
PknB-IN-2

Biological Activity

[Description]:

PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC50 of 12.1 μM[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

IC50: 12.1 μM (PknB)[1]

[In Vitro]

PknB-IN-2 (Compound 10) shows encouraging growth inhibition activity toward the M. tuberculosis H37Rv strain, with a MIC value of 6.2 μg/mL[1].

[References]

[1]. Thongdee P, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₃₂N₂O₄

[ Molecular Weight ]:
460.56

Related Compounds

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