2,4,5-trimethoxybenzoic acid

Names

[ CAS No. ]:
490-64-2

[ Name ]:
2,4,5-trimethoxybenzoic acid

[Synonym ]:
Benzoic acid,2,4,5-trimethoxy
Benzoic acid, 2,4,5-trimethoxy-
EINECS 207-715-9
2,4,5-Trimethoxy-benzoesaeure
2,3-DIHYDRO-3-OXO-1H-INDENE-5-CARBONITRILE
2,4,5-trimethoxy-benzoicaci
2,4,5-Trimethoxybenzoic
RARECHEM AL BO 0322
ASARONIC ACID
Asaronsaeure
MFCD00002435
2,4,5-trimethoxybenzoic acid

Biological Activity

[Description]:

2,4,5-Trimethoxybenzoic acid is a compound identified in purple perilla extracts. 2,4,5-Trimethoxybenzoic acid inhibits M1 macrophage phenotype-mediated inflammation in diabetes[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Oh H, et al. Asaronic Acid Attenuates Macrophage Activation toward M1 Phenotype through Inhibition of NF-κB Pathway and JAK-STAT Signaling in Glucose-Loaded Murine Macrophages. J Agric Food Chem. 2019;67(36):10069-10078.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
300.0±0.0 °C at 760 mmHg

[ Melting Point ]:
143-145 °C(lit.)

[ Molecular Formula ]:
C₁₀H₁₂O₅

[ Molecular Weight ]:
212.199

[ Flash Point ]:
134.0±20.0 °C

[ Exact Mass ]:
212.068466

[ PSA ]:
64.99000

[ LogP ]:
1.52

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.524

[ Water Solubility ]:
SOLUBLE

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Quantitative phosphorus-31 NMR analysis of lignins, a new tool for the lignin chemist. Argyropoulos DS.

J. Wood Chem. Technol. 14(1) , 45-63, (1994)

A new synthesis of asaronic acid and aldehyde and their derivatives. Rajagopalan S, et al.

Proc. Indian Acad. Sci. A 30(5) , 265-270, (1949)