1,2,4-Trimethoxybenzene

Names

[ CAS No. ]:
135-77-3

[ Name ]:
1,2,4-Trimethoxybenzene

[Synonym ]:
1,4,5-trimethoxybenzene
2,4,5-trimethoxybenzene
Benzene,1,2,4-trimethoxy
EINECS 205-219-7
Benzene, 1,2,4-trimethoxy-
1,2,4-trimethoxy benzene
1,2,4-Trimethoxybenzene
MFCD00008360
Hydroxyhydroquinone trimethyl ether

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
247.0±0.0 °C at 760 mmHg

[ Melting Point ]:
19 - 21ºC

[ Molecular Formula ]:
C₉H₁₂O₃

[ Molecular Weight ]:
168.190

[ Flash Point ]:
77.9±19.1 °C

[ Exact Mass ]:
168.078644

[ PSA ]:
27.69000

[ LogP ]:
1.80

[ Vapour Pressure ]:
0.0±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.485

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DC2770000

[ HS Code ]:
29093090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site.

Bioorg. Med. Chem. 19 , 1381-9, (2011)

Carbonic anhydrases (CAs, EC 4.2.1.1) are inhibited by sulfonamides, inorganic anions, phenols, coumarins (acting as prodrugs) and polyamines. A novel class of CA inhibitors (CAIs), interacting with t...