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431884-01-4

Names

[ CAS No. ]:
431884-01-4

[ Name ]:
431884-01-4

Biological Activity

[Description]:

Antimalarial agent 13 (Compound 1) is a potent antimalarial agent. Antimalarial agent 13 shows inhibition with EC50 values of 124 nM and 2.5 μM against P. falciparum parasite and HepG2, respectively[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Gilson PR, et al. Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity. J Med Chem. 2017 Feb 9;60(3):1171-1188.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H15ClN4O

[ Molecular Weight ]:
350.81

Related Compounds