5-iodo-1,3-dimethyluracil
Names
[ CAS No. ]:
40738-83-8
[ Name ]:
5-iodo-1,3-dimethyluracil
[Synonym ]:
5-iodo-1,3-dimethylpyrimidine-2,4-dione
MFCD00192228
5-Iodo-1,3-dimethyluracil
Chemical & Physical Properties
[ Density]:
2.04g/cm3
[ Boiling Point ]:
261.3ºC at 760 mmHg
[ Melting Point ]:
225ºC
[ Molecular Formula ]:
C6H7IN2O2
[ Molecular Weight ]:
266.03600
[ Flash Point ]:
111.8ºC
[ Exact Mass ]:
265.95500
[ PSA ]:
44.00000
[ Index of Refraction ]:
1.665
[ Storage condition ]:
Room temperature.
[ Water Solubility ]:
DMSO: soluble10mg/mL(lit.)
MSDS
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H312-H317-H332-H334-H361
[ Precautionary Statements ]:
P261-P280-P342 + P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
20/21/22-42/43-63
[ Safety Phrases ]:
22-26-36/37/39-45
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933599090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Eur. J. Nucl. Med. Mol. Imaging 29(4) , 499-505, (2002)
5-Iodo-2'-deoxyuridine (IdUrd), a thymidine (TdR) analogue, can be radiolabelled with iodine-125, an Auger radiation emitter, to provoke double-strand breaks once incorporated into DNA of cancer cells...
Synthesis and biological evaluation of new benzo-thieno[3,2-d]pyrimidin-4-one sulphonamide thio-derivatives as potential selective cyclooxygenase-2 inhibitors.Mol. Divers. 17(3) , 445-58, (2013)
The aim of this work was to evaluate the potential anti-inflammatory activity of eleven (5-15) new synthesized derivatives of benzo-thieno[3,2-d]pyrimidine on two cell models, namely human keratinocyt...
Organic iodine (I, III, and V) chemistry: 10 years of development at the Medical University of Warsaw, Poland. Skulski L.Molecules 5(12) , 1331-71, (2000)