(R)-fenfluramine

Names

[ Name ]:
(R)-fenfluramine

[Synonym ]:
Levofenfluramina
Fenfluramine l-form
Levofenfluraminum
Levofenfluramine
l-Fenfluramine
dextrofenfluramine
dexfenfluramine
(2R)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine

Chemical & Physical Properties

[ Density]:
1.078g/cm3

[ Boiling Point ]:
243.1ºC at 760mmHg

[ Molecular Formula ]:
C₁₂H₁₇ClF₃N

[ Molecular Weight ]:
267.71800

[ Flash Point ]:
100.8ºC

[ Exact Mass ]:
267.10000

[ PSA ]:
12.03000

[ LogP ]:
4.43880

[ Index of Refraction ]:
1.455

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SH6824000

CHEMICAL NAME :: Phenethylamine, N-ethyl-alpha-methyl-m-trifluoromethyl-, l-

CAS REGISTRY NUMBER :: 37577-24-5

LAST UPDATED :: 198910

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H16-F3-N

MOLECULAR WEIGHT :: 231.29

WISWESSER LINE NOTATION :: FXFFR CY1&1M2 -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 195 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 161,206,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 77 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 161,206,1966

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311 + H331

[ Precautionary Statements ]:
Missing Phrase - N15.00950417-P261-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
23/24/25

[ Safety Phrases ]:
22-26-36

[ RIDADR ]:
UN 2811 6.1/PG 3

[ RTECS ]:
SH6824000

[ HS Code ]:
2921499090

Customs

[ HS Code ]: 2921499090

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Desorption corona beam ionisation (DCBI), the relatively novel ambient mass spectrometry (MS) technique, was utilised to screen for illicit additives in weight-loss food. The five usually abused chemi...

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In light of recent studies suggesting that amphetamine (AMPH) increases electrically evoked dopamine release ([DA]o), we examined discrepancies between these findings and literature that has demonstra...