TFIIH Modulator19
Names
[ CAS No. ]:
363-03-1
[ Name ]:
TFIIH Modulator19
[Synonym ]:
PHENYL-P-BENZOQUINONE
2-phenylcyclohexa-2,5-diene-1,4-dione
EINECS 206-654-5
Chemical & Physical Properties
[ Density]:
1.1336 (rough estimate)
[ Boiling Point ]:
278.14°C (rough estimate)
[ Melting Point ]:
111-115 °C
[ Molecular Formula ]:
C12H8O2
[ Molecular Weight ]:
184.19100
[ Exact Mass ]:
184.05200
[ PSA ]:
34.14000
[ LogP ]:
1.77800
[ Appearance of Characters ]:
Chunks and Powder | Yellow-brown
[ Index of Refraction ]:
1.6086 (estimate)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DK6650000
- CHEMICAL NAME :
- p-Benzoquinone, phenyl-
- CAS REGISTRY NUMBER :
- 363-03-1
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C12-H8-O2
- MOLECULAR WEIGHT :
- 184.20
- WISWESSER LINE NOTATION :
- L6V DVJ XR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 110 mg/m3/4H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - effect, not otherwise specified Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 19 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 5 mg/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes
- TYPE OF TEST :
- DNA damage
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 5 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 259,1,1991
Safety Information
[ Hazard Codes ]:
Xn;Xi
[ Risk Phrases ]:
R20/21/22;R36/37/38;R42/43
[ Safety Phrases ]:
S26;S36;S37/S39
[ RTECS ]:
DK6650000
[ HS Code ]:
2914399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914399090
[ Summary ]:
2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%